or null mice ［J］. Arterioscler Thromb Vasc Biol, 2002,22(1):49-54.

［3］ Carey RM, Wang ZQ, Siragy HM. Role of the angiotensin type 2 receptor in the regulation of blood pressure and renal function［J］. Hypertension, 2000,35(1 Pt 2):155-163.

［4］ 李予蓉,商立军,范风云. 成熟心肌细胞的分离与培养方法［J］. 第四军医大学学报,2000,21(6): s153.

［5］ Schneider MD, Lorell BH. AT2, judgment day: Which angiotensin receptor is the culprit in cardiac hypertrophy ［J］. Circulation, 2001,104:247-248.

［6］ Oliviero P, Chassagne C, Kolar F, et al. Effect of pressure overload on angiotensin receptor expression in the rat heart during early postnatal life ［J］. J Mol Cell Cardiol, 2000,32(9):1631-1645.

［7］ Zhu YZ, Zhu YC, Li J, et al. Effects of losartan on haemodynamic parameters and angiotensin receptor mRNA levels in rat heart after myocardial infarction ［J］. J Renin Angiotensin Aldosterone Syst, 2000,1(3):257-262.

［8］ Xu J, Carretero OA, Liu YH, et al. Role of AT2 receptors in the cardioprotective effect of AT1 antagonists in mice ［J］. Hypertension, 2002, 40(3):244-250.

［9］ Bartunek J, Weinberg EO, Tajima M, et al. Angiotensin II type 2 receptor blockade amplifies the early signals of cardiac growth response to angiotensin II in hypertrophied hearts ［J］. Circulation, 1999, 99(1):22-25.

［10］ Yang Z, Bove CM, French BA, et al. Angiotensin II type 2 receptor overexpression preserves left ventricular function after myocardial infarction ［J］. Circulation, 2002, 106(1):106-111.

［11］ Yan X, Price RL, Nakayama M, et al. Ventricular?specific expression of angiotensin II type 2 receptors causes dilated cardiomyopathy and heart failure in transgenic mice ［J］. Am J Physiol Heart Circ Physiol, 2003, 285(5):H2179-H2187.

［12］ Li C, Cao L, Zeng Q, et al. Taurine may prevent diabetic rats from developing cardiomyopathy also by downregulating angiotensin II type2 receptor expression ［J］. Cardiovasc Drugs Ther, 2005, 19(2): 105-112.