分枝杆菌药物外排泵及其在耐药机制中作用(3)
作者：佚名； 更新时间：2014-12-13
sca MR,Guglierame P,De Rossi E,et al. mmpL 7 gene of mycobacterium tuberculosis is responsible for isoniazid efflux in mycobacterium smegmatis［J］.Antimicrobial Agents and Chemotherapy,2005,49(11):4775-4777.
〔19〕Braibant M,Gilot P,Content J.The ATP binding cassette(ABC) transport system of mycobacterium tuberculosis.FEMS Microbiol Rev,2000,24(4):449-467.
〔20〕Choudhuri BS,Bhakta S,Barik R,et al.Overexpression and functional characterization of an ABC (ATP-binding cassette) transporter encoded by the genes drrA and drrB of mycobacterium tuberculosis〔J〕.Biochem J,2002,367:279-285.
〔21〕Bhatt k,Banerjee SK, Chakraborti PK.Evidence that phosphate specific transporter is amplified in a fluoroquinolone resistant Mycobacterium smegmatis［J］.Eur J Biochem,2000,267:4028-4032.
〔22〕Poole K. Efflux-mediated resistance to fluroquinolones in Gram-positive bacteria and the mycobacteria［J］.Antimicrob Agents Chemother,2000,44(10):2595-2599.
〔23〕Pasca MR,Guglierame P,Arcesi F,et al.Rv2686c-Rv2687c-Rv2688c,an ABC fluoroquinolone efflux pump in mycobacterium tubercolusis［J］.Antimicrobial Agents and Chemotherapy,2004,48(8):3175-3178.
〔24〕De Rossi E,Branzoni M,Cantoni R,et al.mmr,a mycobacterium tuberculosis gene conferring resistance to small cationic dyes and inhibitors［J］.Journal of Bacteriology,1998,180(22):6068-6071.
〔25〕Buroni S,Manina G,Guqlierame P，et al. LfrR is a repressor that regulates expression of the efflux pump LfrA in mycobacterium smegmatis［J］.Antimicrob Agents Chemother,2006:00656-06v1.
〔26〕Bigi F,Alito A ,Romano M.I,et al.The gene encoding P27 lipoprotein and a putative antibiotic-resistance gene form an operon in mycobacterium tuberculosis and mycobacterium bovis［J］.Microbiology,2000,146:1011-1018.
〔27〕Bigi F,Gioffre A,Klepp L,et al.The knockout of the lprG-Rv1410 operon produces strong attenuation of mycobacterium tuberculosis［J］.Microbes and Infection,2004，182-187.
〔19〕Braibant M,Gilot P,Content J.The ATP binding cassette(ABC) transport system of mycobacterium tuberculosis.FEMS Microbiol Rev,2000,24(4):449-467.
〔20〕Choudhuri BS,Bhakta S,Barik R,et al.Overexpression and functional characterization of an ABC (ATP-binding cassette) transporter encoded by the genes drrA and drrB of mycobacterium tuberculosis〔J〕.Biochem J,2002,367:279-285.
〔21〕Bhatt k,Banerjee SK, Chakraborti PK.Evidence that phosphate specific transporter is amplified in a fluoroquinolone resistant Mycobacterium smegmatis［J］.Eur J Biochem,2000,267:4028-4032.
〔22〕Poole K. Efflux-mediated resistance to fluroquinolones in Gram-positive bacteria and the mycobacteria［J］.Antimicrob Agents Chemother,2000,44(10):2595-2599.
〔23〕Pasca MR,Guglierame P,Arcesi F,et al.Rv2686c-Rv2687c-Rv2688c,an ABC fluoroquinolone efflux pump in mycobacterium tubercolusis［J］.Antimicrobial Agents and Chemotherapy,2004,48(8):3175-3178.
〔24〕De Rossi E,Branzoni M,Cantoni R,et al.mmr,a mycobacterium tuberculosis gene conferring resistance to small cationic dyes and inhibitors［J］.Journal of Bacteriology,1998,180(22):6068-6071.
〔25〕Buroni S,Manina G,Guqlierame P，et al. LfrR is a repressor that regulates expression of the efflux pump LfrA in mycobacterium smegmatis［J］.Antimicrob Agents Chemother,2006:00656-06v1.
〔26〕Bigi F,Alito A ,Romano M.I,et al.The gene encoding P27 lipoprotein and a putative antibiotic-resistance gene form an operon in mycobacterium tuberculosis and mycobacterium bovis［J］.Microbiology,2000,146:1011-1018.
〔27〕Bigi F,Gioffre A,Klepp L,et al.The knockout of the lprG-Rv1410 operon produces strong attenuation of mycobacterium tuberculosis［J］.Microbes and Infection,2004，182-187.
