14、Othsu A,Baba H,SakataY,et al.Phase II study of s-l,a novel oral fluoropyfin idine derivative in patients with metastatic colorectal cancer.Br J Cancer,2000,83:141-145.
15、Miwa M,Ura M, Nish idaM,et al.Design of a norel oral fluoropyrinidine carbamate,capecitabine, which generatess 5- fluorouracil selectively in tumours by enzymes concentra ted in human liver and cancer tissue. Eur J Cancer,1998,34:1274一1281.
16、M iyadera K,Sum izawa T,Haraguchi M,et al.Role of thymidine phosphory lase aetivity in the angiogenic effeet of platelet derived endothelial cell growth faetor/thym idine phosphorylase.Cancer Res,1995,55:1687-1690.
17、Mettem J,Koommagi R,Volm M.Bionlogical charaeterization of subgroups of squamous cell lung carcinomas.Clin Caneer Res,1999,5:1459.
18、Koizumi W,Salgenji K,Nakamaru N,et al.Prediction of response to 5-deoxy-5-fiuorouridine(5- DFUR)in patiens with inoperable advance.gastric cancer by immunostaining of thylnidine phosphorylase/plateletderived endothelial cell growth factor.Oncology, 1999,56:215.
19、 Cutsem EV,Findlay M,Osterwalder B,et al.Capecitabine, an oral fluoropyrimidine
Carbamate with substantial activity in advanced colorectal cancer:Results of a randomized phase II study.J Clin Oncol,2000,18:1337~1345.
20、 Hoff PM,Ansari R,Batist G,et al.Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first- line treatment in 605 patients with metastatic coloreetal cancer:Reusults of a randomized Phase III study.J Clin Oncol,2001,19:2282-2292.
21、张军,王严庆,吴凯南.甲酰四氢叶酸钙对5-Fu的增效作用及在结直肠癌化疗中的应用,国外医学外科学分册,1996,23:340-344.
22、刘新春,程玉峰,李得爱.实用抗肿瘤药物治疗学.北京:人民卫生出版社,2001.636.
23、林万隆.奥沙利铂的药理作用及临床应用,中国肿瘤临床,2000,27:872-874.
24、Bleierg H.Oxaliplatin(L-OHP):a new reality in colorectal cancer. Br J Cancer,1998,77:l-3.
25、BecouarnY, Rougier P.Clinical efficacy of oxaliplatin monotherapy:phase trials
in advanced colorectal cancer, Semin oncol,1998,25:23-31.
26、 Jin ML,Chen Q, Cheng FQ,et al.Oxaliplatin(OXA) in combination with LV/5- FU2 inChinese patients with advanced gastric cancer(AGC).Proc ASCO,2002,21:558-560.
27、Raymond E,Faivre S, Woynarow ski JM,et al.Oxaliplatin in echanism of action and antineoplastic activity.Semin oncol,1998,25:4-12.
28、刘基巍,班丽英,高亚杰,等.国产奥沙利铂治疗结直肠癌II期临床研究.临床肿瘤杂志,2000,5:178-180.
29、金憋林,陈强,程凤歧,等.奥沙利铂联合亚叶酸钙和5-氟尿嘧啶治疗晚期胃癌的研究.中华肿瘤杂志,2003, 25:172- 174.
30、Louvet C,De gramant A.Role and value of oxaliplatin in metastatic colorectal cancers.Rev Med Inteme,1997,18:368一371.
31、孙燕,管忠震,金懋林,等.奥沙利铂单药或与氟尿嘧啶-甲酰四氢叶酸联合应用治疗晚期结直肠癌II期临床试用报告.癌症,1999,18:237-240.
32、Weh HJ, Wilke HJ,Dierlamm J,et al.Weekly therapy with folinic acid(FA) and high-dose 5-fluorouracil(5- Fu)24- hour infusion in pretreated patients with metastatic colorectal carcinoma.A multicenter study by the Association of Medical Oncology of the German Cancer Soeiety(AIO). Ann Oncol,1994,5:233-237.
33、Andre T,ColinP,Louvet C,et al.Semimonthly versus monthly regimen of fluorouracil and leucovorin administered for 24 or 36 weeks as adjuvant therapy in stage II and III colon cancer:results of a randomized trial.J Clin Oncol,2003,21:2896-2903.
34、Lokich JJ, Ahlgren JD,Gullo JJ,etal. A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma:a Mid- Atlantic Oncology program study.J Clin Oncol, 19897:425-432.
35、Kohne CH,Wils J,Lorenz M,et al.Randomized phase IIIstudy of high-dose fluorouracil given as a weekly 24- hour infusion with or without leucovorin versus bolus fluorouracil plus leucovorin in advanced colorectal cancer:European organization of Rese